Breast Cancer Research

Triple negative breast cancer: breast cancer research in evolution.

A 2011 Pubmed search on the terms “breast cancer” and “triple negative” identified 932 articles, thus interest in this topic since the classification of triple negative/basal-like breast cancer has exploded and a number of recent informative reviews have been published [1–3]. We envision this special edition of Breast Disease focused on triple negative breast cancer (TNBC) as a “go-to” handbook...

California Breast Cancer Research Program

Biomarker research in breast cancer.

Breast cancer is a heterogeneous disease with vast differences between patients regarding treatment response and prognosis. Therefore, strategies for individualizing care are needed. The rapid developments in biomarker research in breast cancer are making personalized breast cancer therapy a reality. A biomarker is defined as an objectively measured characteristic that can be evaluated as an in...

Translational research in breast cancer.

Translational research (TR) involves both the development of novel diagnostics and novel therapeutics. These two major developmental areas are often associated with each other and these associations often bring new paradigms in the management of cancer patients. For example, the development of trastuzumab-based treatments has been conducted in harmony with the development of new methodologies t...

Translational research in breast cancer.

routine. This also explains the interest of a larger public in these issues; breast cancer activists are willing to take up a role in the creation of biological and clinical databases. Patients are asked to lobby for and help in clinical studies. On the other hand, the access to human tissues is only possible via the patient. The discussion around the Human Tissue Act in Britain may serve as on...